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The TREMIN Research Program on Women's Health

Overview

The TREMIN Research Program on Women's Health (formerly known as The TREMIN Trust) is one of the world's oldest ongoing research programs dedicated to studying women's health. Initiated in 1934 by Dr. Alan E. Treloar at the University of Minnesota, this unique, intergenerational study was established to document the normal menstrual cycle. It has followed several thousand women throughout their reproductive lives.

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TREMIN participants provide a wide variety of information related to menstruation and health. Initially, 2,350 University of Minnesota women volunteered to participate in the study. A second group of 1,600 women was enrolled between 1961-1963. In 1965, a panel of 1,000 native Alaskan women was invited to participate in the program. Women in the study range from their teens to mid-nineties and represent fifty states and twenty-five foreign countries.

The TREMIN Research Program on Women's Health is a longitudinal and intergenerational study. To date, there are 555 mother-daughter families, 95 mother-daughter-granddaughter families and 3 mother-daughter-granddaughter / great-granddaughter families in the database. TREMIN women have been unfailingly committed to the project with an 80-90 percent return rate on mailings. At present, 1,210 women are active record keepers.

TREMIN Research Program on Women's Health Timeline


1934 The TREMIN Research Program on Women's Health initiated under the directorship of Dr. Alan Treloar at the University of Minnesota.
1934-1939 First panel of participants. 2,350 students was recruited at the University of Minnesota.
1961-1963 Second panel of 1,367 women was recruited at the University of Minnesota.
1965 Panel of 1,000 Alaskan (Eskimo, Aleut & Native Indian) women and girls was recruited to study seasonal variation on the menstrual cycle. Later, 170 urban Caucasian women were added.
1984 After Dr. Treloar's retirement, the TREMIN program moved to the University of Utah under the direction of Dr. Ann Voda.
1990 505 premenopausal women from the TREMIN program and Douglass College (Rutgers University) were recruited into an ongoing longitudinal study of the menopausal transition (The Midlife Women's Health Survey).
1998

After Dr. Voda's retirement, the TREMIN program moved to The Pennsylvania State University under the direction of Dr. Phyllis Kernoff Mansfield.

Approximately 140 midlife TREMIN participants (25-58 years old) were enrolled in a 5-year NIH-funded study of reproductive aging (BIMORA). These women collect daily urine samples for 6 months/year which are measured for estrogen, progesterone, FSH and LH.

Intergenerational Participants:
To date, there are 555 mother-daughter families, 95 mother-daughter-granddaughter families and 3 mother-daughter-granddaughter-greatgranddaughter families in the database.

Presently, 1,210 women from all groups, early teens to mid-90's, are active record keepers.

To learn more about gaining access to this data, please see our page on this topic. Please address all correspondence to tremin@pop.psu.edu.

Last modified: 02/24/06 | Contact Webmaster